Figure 3

The averaged single-unit response to laser stimulation for each brain region of interest at differing stimulation intensity levels (A) and averaged for all intensity levels (B). (A) Mean firing rate increased with stimulus intensity (120-180 mJ) for all the recorded regions (ACC, MD, SI, and VPL). Each panel represents the averaged firing rate of neurons around the time of laser stimulation (1.0 s pre- to 1.0 s post-stimulus). The dashed lines indicate 99% confidence limits. (B) When the single-unit responses are pooled across all the intensity levels (120-180 mJ), a double-peak response can be seen in all the recorded regions with a short-latency peak of less than 100 ms and a long-latency of 300-500 ms.