Mechano- and heat nociceptive behaviour. A. Reaction time in seconds of Advillin-Cre mice and their wildtype littermates during the hotplate test (p = 0.151). B. Latency to paw withdrawal in seconds during the dynamic plantar test (p = 0.699). C. Force applied at moment of paw withdrawal during the dynamic plantar test (p = 0.122). Data are expressed in mean ± SEM.