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Table 1 Comparisons of the biophysical properties of lamina I/II sodium channel currents to recombinant sodium channels

From: Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons

NaV Type

Activation

V0.5 (mV)

Fast Inactivation

V0.5 (mV)

Slow Inactivation

V0.5 (mV)

Recovery from Inactivation

Ï„ at -80 mV (ms)

Development of Inactivation

Ï„ at -70 mV (ms)

DRG TTX-S NaV (Axotomized Rats)

-29

-72

 

34

156

Lamina I/II Na V

-34

-69

-58

27

51

NaV1.3

-26

-65

 

60

149

NaV1.2

-22

-61

 

18

33

NaV1.7

-26

-78

 

113

147

  1. Bolded data are from the current study, while axotomized DRG, NaV1.3, NaV1.2, and NaV1.7 data are from [24].