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Table 1 Comparisons of the biophysical properties of lamina I/II sodium channel currents to recombinant sodium channels

From: Identification of sodium channel isoforms that mediate action potential firing in lamina I/II spinal cord neurons

NaV Type Activation
V0.5 (mV)
Fast Inactivation
V0.5 (mV)
Slow Inactivation
V0.5 (mV)
Recovery from Inactivation
τ at -80 mV (ms)
Development of Inactivation
τ at -70 mV (ms)
DRG TTX-S NaV (Axotomized Rats) -29 -72   34 156
Lamina I/II Na V -34 -69 -58 27 51
NaV1.3 -26 -65   60 149
NaV1.2 -22 -61   18 33
NaV1.7 -26 -78   113 147
  1. Bolded data are from the current study, while axotomized DRG, NaV1.3, NaV1.2, and NaV1.7 data are from [24].