TRPV1 mRNA and protein levels in the pre/infra-limbic cortex of sham and SNI rats. "A" shows the unchanged TRPV1 mRNA levels normalized vs β-actin in neuropathic vs sham rats. "B" shows the enhanced TRPV1 protein levels normalized vs β-actin in neuropathic vs sham rats. "C" shows the increased TRPV1 staining in the layer II-III of the rat pre/infra-limbic cortex. Data are represented as a mean ± SEM n = 3 rats per group. P < 0.05 was considered statistically significant. ANOVA, post hoc Tukey. Scale bars = 100 μm.