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Table 1 Quantification of western blots on ipsilateral vs contralateral L4 (uninjured) DRGs from SNL rats 17 days post-surgery.

From: Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

RAT SNL
Uninjured L4 DRG vs. Contralateral
  Contra Contra Ipsi Ipsi  
Protein/Standardization Mean % SEM Mean % SEM P-value
p-mTOR/mTOR 100 17.9 402.8 63.6 0.001
p-mTOR/beta III tubulin 100 19.0 425.7 92.0 0.012
mTOR/beta III tubulin 100 12.1 86.0 34.4 NS
p-4EBP/4EBP 100 11.6 100.1 9.3 NS
p-4EBP/beta III tubulin 100 15.8 190.3 22.2 0.003
4EBP/beta III tubulin 100 17.8 182.6 14.8 0.002
p-ERK/ERK 100 11.0 121.0 17.1 NS
p-ERK/beta III tubulin 100 19.8 111.3 13.2 NS
ERK/beta III tubulin 100 12.3 97.2 4.0 NS
p-eIF4alpha/eIF4alpha 100 13.5 60.1 8.0 0.026
p-eIF2alpha/beta III tubulin 100 19.7 61.8 7.2 NS
eIF2alpha/beta III tubulin 100 13.6 106.9 6.3 NS
mov10/beta III tubulin 100 20.8 220.9 37.0 0.008
rck/beta III tubulin 100 12.5 123.5 14.1 NS
eIF4A/beta III tubulin 100 15.3 102.5 14.7 NS
fbxw7/beta III tubulin 100 45.1 102.3 30.5 NS
p-AKT/total AKT 100 10.9 112.8 14.7 NS
p-AKT/beta III tubulin 100 6.0 107.8 12.2 NS
AKT/beta III tubulin 100 10.8 92.5 3.9 NS
p-mTOR/GAPDH 100 14.1 387.2 72.4 0.006
p-4EBP/GAPDH 100 13.3 162.6 12.0 0.002
4EBP/GAPDH 100 11.8 163.1 9.6 0.000
mov10/GAPDH 100 19.4 195.6 34.6 0.025