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Table 3 Quantification of western blots on ipsilateral vs. contralateral sciatic nerves from SNL rats 17 days post-surgery.

From: Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain

RAT SNL
Sciatic Nerve Ipsilateral vs. Contralateral
  Contra Contra Ipsi Ipsi  
Protein/Standardization Mean % SEM Mean % SEM P-value
p-mTOR/mTOR 100 27.6 581.8 112.0 0.002
p-4EBP/4EBP 100 8.9 117.0 13.6 NS
p-4EBP/4EBP 100 12.6 408.0 104.2 0.008
p-rS6/beta III-tubulin 100 22.6 1005.5 300.0 0.007
p-AKT/AKT 100 17.3 101.6 22.0 NS
p-AKT/beta III-tubulin 100 14.4 276.4 67.5 0.034
AKT/beta III-tubulin 100 11.2 261.6 36.9 0.003
p-ERK/ERK 100 8.8 510.3 153.4 0.023
p-eIF4E/eIF4E 100 14.8 164.0 17.6 0.024
p-eIF4E/beta III-tubulin 100 25.1 700.8 168.5 0.008
eIF4E/beta III-tubulin 100 16.8 415.4 62.7 0.001
eIF4A/beta III-tubulin 100 14.6 241.0 31.0 0.001
p-eIF2alpha/eIF2alpha 100 8.9 110.7 21.4 NS
p-eIF2alpha/beta III-tubulin 100 15.3 506.4 163.4 0.024
eIF2alpha/beta III-tubulin 100 19.5 575.7 107.9 0.001
FMRP/beta III-tubulin 100 14.2 257.8 59.0 0.024
mov10/beta III-tubulin 100 28.5 636.3 161.2 0.008
rck/beta III-tubulin 100 22.9 483.4 141.4 0.015
fbxw7/beta III-tubulin 100 37.7 305.7 72.9 0.028
p-4EBP/GAPDH 100 25.4 224.6 18.6 0.004
4EBP/GAPDH 100 26.1 257.4 32.5 0.006
p-eIF4E/GAPDH 100 15.9 458.0 54.4 0.000
eIF4E/GAPDH 100 10.6 270.2 12.4 0.000
p-eIF2alpha/GAPDH 100 10.3 297.4 74.9 0.018
eIF2alpha/GAPDH 100 4.7 244.3 15.7 0.000
rck/GAPDH 100 20.5 280.0 62.2 0.013
p-AKT/GAPDH 100 8.4 182.8 26.1 0.017
AKT/GAPDH 100 14.1 177.2 18.6 0.011
eIF4A/GAPDH 100 9.3 249.6 33.0 0.001
fbxw7/GAPDH 100 25.4 420.6 134.1 0.037