Figure 5
From: Involvement of peripheral ionotropic glutamate receptors in orofacial thermal hyperalgesia in rats
The rostro-caudal distribution (A, B, C, D, E and F) and mean number (G and H) of pERK-IR cells in Vc and C1-C2 following cold stimulation of the tongue (A, B, C and G) or whisker pad skin (D, E, F and H) in the rats with Glu (0.1 M or 0.5 M) or vehicle injection into the tongue or whisker pad skin. Note that significantly larger number of pERK-IR cells was observed in tongue Glu-injected rats compared with that in whisker Glu-injected rats. *: p < 0.05, **: p < 0.01.