Figure 8
From: Involvement of peripheral ionotropic glutamate receptors in orofacial thermal hyperalgesia in rats
Mean number of pERK-IR cells in Vc and C1-C2 following heat (A) or cold (B) stimulation of the tongue or whisker pad skin in the rats with 0.5 M Glu and Veh, 1 mM APV or 10 μM CNQX injections into the tongue or whisker pad skin. Note that the mean number of pERK-IR cells following cold stimulation of the tongue but not whisker pad skin was significantly smaller in the rats with Glu- and APV- or CNQX-injected rats than that with Veh injected. *: p < 0.05, **: p < 0.01.