Table 1 Values of rate constants of P2X3 receptor kinetic model in mouse trigeminal neurons
Rate Constant | Control | + MβCD |
|---|---|---|
k1 | 24000 (mM-1·s-1) | 24000 (mM-1·s-1) |
l1 | 15 (s-1) | 15 (s-1) |
k2 | 16000 (mM-1·s-1) | 16000 (mM-1·s-1) |
l2 | 30 (s-1) | 30 (s-1) |
k3 | 8000 (mM-1·s-1) | 8000 (mM-1·s-1) |
l3 | 45 (s-1) | 45 (s-1) |
k4 | 75 (s-1) | 40 (s-1) |
l4 | 10 (s-1) | 10 (s-1) |
m1 | 24000 (mM-1·s-1) | 24000 (mM-1·s-1) |
n1 | 0.01 (s-1) | 0.019 (s-1) |
m2 | 16000 (mM-1·s-1) | 16000 (mM-1·s-1) |
n2 | 0.02 (s-1) | 0.038 (s-1) |
m3 | 8000 (mM-1·s-1) | 8000 (mM-1·s-1) |
n3 | 0.03 (s-1) | 0.057 (s-1) |
m4 | 0.001 (s-1) | 0.001 (s-1) |
n4 | 0.44 (s-1) | 0.68 (s-1) |
d1 | 0.00001 (s-1) | 0.00001 (s-1) |
r1 | 10 (s-1) | 10 (s-1) |
d2 | 0.12 (s-1) | 0.12 (s-1) |
r2 | 0.00001 (s-1) | 0.00001 (s-1) |
d3 | 0.00001 (s-1) | 0.00001 (s-1) |
r3 | 0.00001 (s-1) | 0.00001 (s-1) |
d4 | 0.00001 (s-1) | 0.00001 (s-1) |
r4 | 0.00001 (s-1) | 0.00001 (s-1) |
d5 | 9.0 (s-1) | 13.0 (s-1) |
r5 | 1.1 (s-1) | 1.1 (s-1) |