Figure 7From: Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat Effect of spinal PKCζ/PKMζ inhibition on Fos expression in the dorsal horn following intraplantar formalin. (a, b) Representative photomicrographs of formalin-induced upregulation of Fos expression in superficial (I-II) and deep laminae (V-VI) of the ipsilateral lumbar dorsal horn in rats pre-treated with intrathecal (a) scrambled peptide (10 μg, n = 5) or (b) ZIP (10 μg, n = 5). (c) Quantification of number of Fos-positive cells in superficial and deep laminae of the lumbar (L4-L6) dorsal horn. All data presented as mean ± s.e.m., ∗ p < 0.05. Scale bars = 100 μm.Back to article page