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Table 1 Primary radioligand competitive binding assays

From: Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands

Ligand (10 μM) Human 5-HT2A (%) Rat 5-HT2C (%) Rat CB1 (%) Human CB2 (%)
NMP4 23.9 -9.3 99.3 104.4
NMP7 ND ND ND ND
NMP139 7.7 -7.8 46.3 51.3
NMP140 11.2 -4.2 79.3 71.1
NMP141 11.9 -8.4 88.6 88.7
NMP144 -5.2 13 67.4 90.6
  1. ND: not determined