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Table 1 Lameness, pathology and hyperalgesia score assessed in sheep before and after treatment.

From: Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia

Sheep i.d. Lame Leg DAY 0 DAY 3
   Lameness Score Pathology Score Emax (%) Lameness Score Pathology Score Emax (%)
Y45 LH 8 4 62.6 2 4 19.2
W140 RH 8 4 47.7 1 4 25.5
G122 LF 7 4 59 3 2 -7.2
R5 RF 7 4 71.4 2 1 19.8
Y36 RH 8 3 29.3 1 1 3.7
G97 LF 6 4 62.9 4 4 62.9
B93 RF 8 2 40.7 1 0 27.9
Y56 RF 6 4 38.5 3 2 41.4
W15 LF 5 3 33.4 4 3 -13.0
237 LH 7 2 29.9 2 0 5.1
G117 RF 6 2 16.7 0 0 8.75
394 LH 4 4 25.5 5 3 3.3
B83a RH 8 4 58.4 - - -
G60a LH 6 4 32.7 - - -
G146a RH 7 3 63.9 - - -
B23a RH 5 2 52.7 - - -
W110a LH 5 2 42.5 - - -
B801a RH 5 2 55.2 - - -
B1b RH 6 3 47.4 3 3 -8.27
RSb RH 5 4 49.5 5 3 48.9
Y192b LH 5 4 52.0 4 3 31.7
B24b RH 4 4 41.0 4 3 -17.5
B69b LH 4 2 31.6 1 1 2.6
B93b LH 4 4 37.6 2 1 2.6
MEAN (± sem)   6.6 ± 0.3   45.1 ± 2.9 2.6 ± 0.3   15.0 ± 4.6
MEDIAN (range)    4 (2-4)    2.5 (0-4)  
  1. Mean lameness (± SEM) and median pathology (range) scores and mean magnitude of hyperalgesia (Emax), represented as the percentage change in response threshold from the non-lame limbs, for 24 sheep affected by unilateral lameness recorded on day 0 before treatment, then on day 3 after treatment. LH-left hindleg; RH-right hindleg; LF-left foreleg; RF-right foreleg; a - sheep euthanased on day 0 before treatment; b - sheep euthanased 3 days after treatment.