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Table 1 Lameness, pathology and hyperalgesia score assessed in sheep before and after treatment.

From: Co-induction of cyclooxyenase-2 and early growth response gene (Egr-1) in spinal cord in a clinical model of persistent inflammation and hyperalgesia

Sheep i.d.

Lame Leg

DAY 0

DAY 3

  

Lameness Score

Pathology Score

Emax (%)

Lameness Score

Pathology Score

Emax (%)

Y45

LH

8

4

62.6

2

4

19.2

W140

RH

8

4

47.7

1

4

25.5

G122

LF

7

4

59

3

2

-7.2

R5

RF

7

4

71.4

2

1

19.8

Y36

RH

8

3

29.3

1

1

3.7

G97

LF

6

4

62.9

4

4

62.9

B93

RF

8

2

40.7

1

0

27.9

Y56

RF

6

4

38.5

3

2

41.4

W15

LF

5

3

33.4

4

3

-13.0

237

LH

7

2

29.9

2

0

5.1

G117

RF

6

2

16.7

0

0

8.75

394

LH

4

4

25.5

5

3

3.3

B83a

RH

8

4

58.4

-

-

-

G60a

LH

6

4

32.7

-

-

-

G146a

RH

7

3

63.9

-

-

-

B23a

RH

5

2

52.7

-

-

-

W110a

LH

5

2

42.5

-

-

-

B801a

RH

5

2

55.2

-

-

-

B1b

RH

6

3

47.4

3

3

-8.27

RSb

RH

5

4

49.5

5

3

48.9

Y192b

LH

5

4

52.0

4

3

31.7

B24b

RH

4

4

41.0

4

3

-17.5

B69b

LH

4

2

31.6

1

1

2.6

B93b

LH

4

4

37.6

2

1

2.6

MEAN (± sem)

 

6.6 ± 0.3

 

45.1 ± 2.9

2.6 ± 0.3

 

15.0 ± 4.6

MEDIAN (range)

  

4 (2-4)

  

2.5 (0-4)

 
  1. Mean lameness (± SEM) and median pathology (range) scores and mean magnitude of hyperalgesia (Emax), represented as the percentage change in response threshold from the non-lame limbs, for 24 sheep affected by unilateral lameness recorded on day 0 before treatment, then on day 3 after treatment. LH-left hindleg; RH-right hindleg; LF-left foreleg; RF-right foreleg; a - sheep euthanased on day 0 before treatment; b - sheep euthanased 3 days after treatment.