TY - JOUR AU - Ferreira, S. H. PY - 1972 DA - 1972// TI - Prostaglandins, aspirin-like drugs and analgesia JO - Nature VL - 240 UR - https://doi.org/10.1038/240200a0 DO - 10.1038/240200a0 ID - Ferreira1972 ER - TY - JOUR AU - Ferreira, S. H. AU - Nakamura, M. PY - 1979 DA - 1979// TI - II - Prostaglandin hyperalgesia: the peripheral analgesic activity of morphine, enkephalins and opioid antagonists JO - Prostaglandins VL - 18 UR - https://doi.org/10.1016/0090-6980(79)90104-7 DO - 10.1016/0090-6980(79)90104-7 ID - Ferreira1979 ER - TY - JOUR AU - Lorenzetti, B. B. AU - Ferreira, S. H. PY - 1985 DA - 1985// TI - Mode of analgesic action of dipyrone: direct antagonism of inflammatory hyperalgesia JO - Eur J Pharmacol VL - 114 UR - https://doi.org/10.1016/0014-2999(85)90383-8 DO - 10.1016/0014-2999(85)90383-8 ID - Lorenzetti1985 ER - TY - JOUR AU - Cunha, T. M. AU - Roman-Campos, D. AU - Lotufo, C. M. AU - Duarte, H. L. AU - Souza, G. R. AU - Verri, W. A. AU - Funez, M. I. AU - Dias, Q. M. AU - Schivo, I. R. AU - Domingues, A. C. AU - Sachs, D. AU - Chiavegatto, S. AU - Teixeira, M. M. AU - Hothersall, J. S. AU - Cruz, J. S. AU - Cunha, F. Q. AU - Ferreira, S. H. PY - 2010 DA - 2010// TI - Morphine peripheral analgesia depends on activation of the PI3Kgamma/AKT/nNOS/NO/KATP signaling pathway JO - P Natl Acad Sci USA VL - 107 UR - https://doi.org/10.1073/pnas.0914733107 DO - 10.1073/pnas.0914733107 ID - Cunha2010 ER - TY - JOUR AU - Ferreira, S. H. AU - Duarte, I. D. AU - Lorenzetti, B. B. PY - 1991 DA - 1991// TI - The molecular mechanism of action of peripheral morphine analgesia: stimulation of the cGMP system via nitric oxide release JO - Eur J Pharmacol VL - 201 UR - https://doi.org/10.1016/0014-2999(91)90333-L DO - 10.1016/0014-2999(91)90333-L ID - Ferreira1991 ER - TY - JOUR AU - Amarante, L. H. AU - Duarte, I. D. PY - 2002 DA - 2002// TI - The kappa-opioid agonist (+/-)-bremazocine elicits peripheral antinociception by activation of the L-arginine/nitric oxide/cyclic GMP pathway JO - Eur J Pharmacol VL - 454 UR - https://doi.org/10.1016/S0014-2999(02)02275-6 DO - 10.1016/S0014-2999(02)02275-6 ID - Amarante2002 ER - TY - JOUR AU - Amarante, L. H. AU - Alves, D. P. AU - Duarte, I. D. PY - 2004 DA - 2004// TI - Study of the involvement of K + channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine JO - Eur J Pharmacol VL - 494 UR - https://doi.org/10.1016/j.ejphar.2004.05.009 DO - 10.1016/j.ejphar.2004.05.009 ID - Amarante2004 ER - TY - JOUR AU - Zimmermann, M. PY - 1983 DA - 1983// TI - Ethical guidelines for investigations of experimental pain in conscious animals JO - Pain VL - 16 UR - https://doi.org/10.1016/0304-3959(83)90201-4 DO - 10.1016/0304-3959(83)90201-4 ID - Zimmermann1983 ER - TY - JOUR AU - Cunha, T. M. AU - Verri, W. A. AU - Vivancos, G. G. AU - Moreira, I. F. AU - Reis, S. AU - Parada, C. A. AU - Cunha, F. Q. AU - Ferreira, S. H. PY - 2004 DA - 2004// TI - An electronic pressure-meter nociception paw test for mice JO - Braz J Med Biol Res VL - 37 UR - https://doi.org/10.1590/S0100-879X2004000300018 DO - 10.1590/S0100-879X2004000300018 ID - Cunha2004 ER - TY - JOUR AU - Vivancos, G. G. AU - Verri, W. A. AU - Cunha, T. M. AU - Schivo, I. R. AU - Parada, C. A. AU - Cunha, F. Q. AU - Ferreira, S. H. PY - 2004 DA - 2004// TI - An electronic pressure-meter nociception paw test for rats JO - Braz J Med Biol Res VL - 37 UR - https://doi.org/10.1590/S0100-879X2004000300017 DO - 10.1590/S0100-879X2004000300017 ID - Vivancos2004 ER - TY - JOUR AU - Hargreaves, K. AU - Dubner, R. AU - Brown, F. AU - Flores, C. AU - Joris, J. PY - 1988 DA - 1988// TI - A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia JO - Pain VL - 32 UR - https://doi.org/10.1016/0304-3959(88)90026-7 DO - 10.1016/0304-3959(88)90026-7 ID - Hargreaves1988 ER - TY - JOUR AU - Linhart, O. AU - Obreja, O. AU - Kress, M. PY - 2003 DA - 2003// TI - The inflammatory mediators serotonin, prostaglandin E2 and bradykinin evoke calcium influx in rat sensory neurons JO - Neuroscience VL - 118 UR - https://doi.org/10.1016/S0306-4522(02)00960-0 DO - 10.1016/S0306-4522(02)00960-0 ID - Linhart2003 ER - TY - JOUR AU - Zhuang, Z. Y. AU - Xu, H. AU - Clapham, D. E. AU - Ji, R. R. PY - 2004 DA - 2004// TI - Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization JO - J Neurosci VL - 24 UR - https://doi.org/10.1523/JNEUROSCI.2893-04.2004 DO - 10.1523/JNEUROSCI.2893-04.2004 ID - Zhuang2004 ER - TY - JOUR AU - Coffer, P. J. AU - Jin, J. AU - Woodgett, J. R. PY - 1998 DA - 1998// TI - Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation JO - Biochem J VL - 335 UR - https://doi.org/10.1042/bj3350001 DO - 10.1042/bj3350001 ID - Coffer1998 ER - TY - JOUR AU - Ko, M. C. AU - Tuchman, J. E. AU - Johnson, M. D. AU - Wiesenauer, K. AU - Woods, J. H. PY - 2000 DA - 2000// TI - Local administration of mu or kappa opioid agonists attenuates capsaicin-induced thermal hyperalgesia via peripheral opioid receptors in rats JO - Psychopharmacology VL - 148 UR - https://doi.org/10.1007/s002130050040 DO - 10.1007/s002130050040 ID - Ko2000 ER - TY - JOUR AU - Baamonde, A. AU - Lastra, A. AU - Juárez, L. AU - García, V. AU - Hidalgo, A. AU - Menéndez, L. PY - 2005 DA - 2005// TI - Effects of the local administration of selective mu-, delta-and kappa-opioid receptor agonists on osteosarcoma-induced hyperalgesia JO - Naunyn Schmiedebergs Arch Pharmacol VL - 372 UR - https://doi.org/10.1007/s00210-005-0013-6 DO - 10.1007/s00210-005-0013-6 ID - Baamonde2005 ER - TY - JOUR AU - Stein, C. AU - Millan, M. J. AU - Shippenberg, T. S. AU - Peter, K. AU - Herz, A. PY - 1989 DA - 1989// TI - Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors JO - J Pharmacol Exp Ther VL - 248 ID - Stein1989 ER - TY - JOUR AU - Rogers, H. AU - Birch, P. J. AU - Harrison, S. M. AU - Palmer, E. AU - Manchee, G. R. AU - Judd, D. B. AU - Naylor, A. AU - Scopes, D. I. AU - Hayes, A. G. PY - 1992 DA - 1992// TI - GR94839, a kappa-opioid agonist with limited access to the central nervous system, has antinociceptive activity JO - Br J Pharmacol VL - 106 UR - https://doi.org/10.1111/j.1476-5381.1992.tb14413.x DO - 10.1111/j.1476-5381.1992.tb14413.x ID - Rogers1992 ER - TY - JOUR AU - Machelska, H. AU - Pflüger, M. AU - Weber, W. AU - Piranvisseh-Völk, M. AU - Daubert, J. D. AU - Dehaven, R. AU - Stein, C. PY - 1999 DA - 1999// TI - Peripheral effects of the kappa-opioid agonist EMD 61753 on pain and inflammation in rats and humans JO - J Pharmacol Exp Ther VL - 290 ID - Machelska1999 ER - TY - JOUR AU - Barber, A. AU - Bartoszyk, G. D. AU - Bender, H. M. AU - Gottschlich, R. AU - Greiner, H. E. AU - Harting, J. AU - Mauler, F. AU - Minck, K. O. AU - Murray, R. D. AU - Simon, M. AU - Seyfried, C. A. PY - 1994 DA - 1994// TI - A pharmacological profile of the novel, peripherally-selective kappa-opioid receptor agonist, EMD 61753 JO - Br J Pharmacol VL - 113 UR - https://doi.org/10.1111/j.1476-5381.1994.tb17142.x DO - 10.1111/j.1476-5381.1994.tb17142.x ID - Barber1994 ER - TY - JOUR AU - Taguchi, R. AU - Taguchi, T. AU - Kitakoji, H. PY - 2010 DA - 2010// TI - Involvement of peripheral opioid receptors in electroacupuncture analgesia for carrageenan-induced hyperalgesia JO - Brain Res VL - 1355 UR - https://doi.org/10.1016/j.brainres.2010.08.014 DO - 10.1016/j.brainres.2010.08.014 ID - Taguchi2010 ER - TY - JOUR AU - Ji, R. R. AU - Zhang, Q. AU - Law, P. Y. AU - Low, H. H. AU - Elde, R. AU - Hökfelt, T. PY - 1995 DA - 1995// TI - Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation JO - J Neurosci VL - 15 ID - Ji1995 ER - TY - JOUR AU - Verri, W. A. AU - Cunha, T. M. AU - Parada, C. A. AU - Poole, S. AU - Cunha, F. Q. AU - Ferreira, S. H. PY - 2006 DA - 2006// TI - Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? JO - Pharmacol Ther VL - 112 UR - https://doi.org/10.1016/j.pharmthera.2006.04.001 DO - 10.1016/j.pharmthera.2006.04.001 ID - Verri2006 ER - TY - JOUR AU - Lima, F. O. AU - Souza, G. R. AU - Verri, W. A. AU - Parada, C. A. AU - Ferreira, S. H. AU - Cunha, F. Q. AU - Cunha, T. M. PY - 2010 DA - 2010// TI - Direct blockade of inflammatory hypernociception by peripheral A1 adenosine receptors: involvement of the NO/cGMP/PKG/KATP signaling pathway JO - Pain VL - 151 UR - https://doi.org/10.1016/j.pain.2010.08.014 DO - 10.1016/j.pain.2010.08.014 ID - Lima2010 ER - TY - JOUR AU - Agarwal, N. AU - Pacher, P. AU - Tegeder, I. AU - Amaya, F. AU - Constantin, C. E. AU - Brenner, G. J. AU - Rubino, T. AU - Michalski, C. W. AU - Marsicano, G. AU - Monory, K. AU - Mackie, K. AU - Marian, C. AU - Batkai, S. AU - Parolaro, D. AU - Fischer, M. J. AU - Reeh, P. AU - Kunos, G. AU - Kress, M. AU - Lutz, B. AU - Woolf, C. J. AU - Kuner, R. PY - 2007 DA - 2007// TI - Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors JO - Nat Neurosci VL - 10 UR - https://doi.org/10.1038/nn1916 DO - 10.1038/nn1916 ID - Agarwal2007 ER - TY - JOUR AU - Zhou, L. AU - Zhang, Q. AU - Stein, C. AU - Schafer, M. PY - 1998 DA - 1998// TI - Contribution of opioid receptors on primary afferent versus sympathetic neurons to peripheral opioid analgesia JO - J Pharmacol Exp Ther VL - 286 ID - Zhou1998 ER - TY - JOUR AU - Bartho, L. AU - Stein, C. AU - Herz, A. PY - 1990 DA - 1990// TI - Involvement of capsaicin-sensitive neurones in hyperalgesia and enhanced opioid antinociception in inflammation JO - Naunyn Schmiedebergs Arch Pharmacol VL - 342 UR - https://doi.org/10.1007/BF00175710 DO - 10.1007/BF00175710 ID - Bartho1990 ER - TY - JOUR AU - Gaveriaux-Ruff, C. AU - Nozaki, C. AU - Nadal, X. AU - Hever, X. C. AU - Weibel, R. AU - Matifas, A. AU - Reiss, D. AU - Filliol, D. AU - Nassar, M. A. AU - Wood, J. N. AU - Maldonado, R. AU - Kieffer, B. L. PY - 2011 DA - 2011// TI - Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia JO - Pain VL - 152 UR - https://doi.org/10.1016/j.pain.2010.12.031 DO - 10.1016/j.pain.2010.12.031 ID - Gaveriaux-Ruff2011 ER - TY - JOUR AU - Leanez, S. AU - Hervera, A. AU - Pol, O. PY - 2009 DA - 2009// TI - Peripheral antinociceptive effects of mu- and delta-opioid receptor agonists in NOS2 and NOS1 knockout mice during chronic inflammatory pain JO - Eur J Pharmacol VL - 602 UR - https://doi.org/10.1016/j.ejphar.2008.11.019 DO - 10.1016/j.ejphar.2008.11.019 ID - Leanez2009 ER - TY - JOUR AU - Hervera, A. AU - Negrete, R. AU - Leanez, S. AU - Martin-Campos, J. M. AU - Pol, O. PY - 2011 DA - 2011// TI - Peripheral effects of morphine and expression of mu-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling JO - Mol Pain VL - 12 ID - Hervera2011 ER - TY - JOUR AU - Picolo, G. AU - Cury, Y. PY - 2004 DA - 2004// TI - Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist JO - Life Sci VL - 75 UR - https://doi.org/10.1016/j.lfs.2003.12.024 DO - 10.1016/j.lfs.2003.12.024 ID - Picolo2004 ER - TY - JOUR AU - Narita, M. AU - Imai, S. AU - Kasukawa, A. AU - Yajima, Y. AU - Suzuki, T. PY - 2004 DA - 2004// TI - Increased level of neuronal phosphoinositide 3-kinase gamma by the activation of mu-opioid receptor in the mouse periaqueductal gray matter: further evidence for the implication in morphine-induced antinociception JO - Neuroscience VL - 124 UR - https://doi.org/10.1016/j.neuroscience.2003.11.023 DO - 10.1016/j.neuroscience.2003.11.023 ID - Narita2004 ER - TY - JOUR AU - Narita, M. AU - Ohnishi, O. AU - Nemoto, M. AU - Yajima, Y. AU - Suzuki, T. PY - 2002 DA - 2002// TI - Implications of phosphoinositide 3-kinase in the mu- and delta-opioid receptor-mediated supraspinal antinociception in the mouse JO - Neuroscience VL - 113 UR - https://doi.org/10.1016/S0306-4522(02)00197-5 DO - 10.1016/S0306-4522(02)00197-5 ID - Narita2002 ER - TY - JOUR AU - König, C. AU - Gavrilova-Ruch, O. AU - von Banchet, G. S. AU - Bauer, R. AU - Grün, M. AU - Hirsch, E. AU - Rubio, I. AU - Schulz, S. AU - Heinemann, S. H. AU - Schaible, H. G. AU - Wetzker, R. PY - 2010 DA - 2010// TI - Modulation of mu opioid receptor desensitization in peripheral sensory neurons by phosphoinositide 3-kinase gamma JO - Neuroscience VL - 169 UR - https://doi.org/10.1016/j.neuroscience.2010.04.068 DO - 10.1016/j.neuroscience.2010.04.068 ID - König2010 ER - TY - JOUR AU - Chiang, H. T. AU - Cheng, W. H. AU - Lu, P. J. AU - Huang, H. N. AU - Lo, W. C. AU - Tseng, Y. C. AU - Wang, J. L. AU - Hsiao, M. AU - Tseng, C. J. PY - 2009 DA - 2009// TI - Neuronal nitric oxide synthase activation is involved in insulin-mediated cardiovascular effects in the nucleus tractus solitarii of rats JO - Neuroscience VL - 159 UR - https://doi.org/10.1016/j.neuroscience.2008.12.048 DO - 10.1016/j.neuroscience.2008.12.048 ID - Chiang2009 ER - TY - JOUR AU - Canabal, D. D. AU - Potian, J. G. AU - Duran, R. G. AU - McArdle, J. J. AU - Routh, V. H. PY - 2007 DA - 2007// TI - Hyperglycemia impairs glucose and insulin regulation of nitric oxide production in glucose-inhibited neurons in the ventromedial hypothalamus JO - Am J Physiol Regul Integr Comp Physiol VL - 293 UR - https://doi.org/10.1152/ajpregu.00207.2007 DO - 10.1152/ajpregu.00207.2007 ID - Canabal2007 ER - TY - JOUR AU - Sánchez-Blázquez, P. AU - Rodríguez-Muñoz, M. AU - Garzón, J. PY - 2010 DA - 2010// TI - Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0011278 DO - 10.1371/journal.pone.0011278 ID - Sánchez-Blázquez2010 ER - TY - JOUR AU - Sachs, D. AU - Cunha, F. Q. AU - Ferreira, S. H. PY - 2004 DA - 2004// TI - Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K + channel pathway JO - P Natl Acad Sci USA VL - 101 UR - https://doi.org/10.1073/pnas.0308382101 DO - 10.1073/pnas.0308382101 ID - Sachs2004 ER - TY - JOUR AU - Rodrigues, A. R. AU - Duarte, I. D. PY - 2000 DA - 2000// TI - The peripheral antinociceptive effect induced by morphine is associated with ATP-sensitive K(+) channels JO - Br J Pharmacol VL - 129 UR - https://doi.org/10.1038/sj.bjp.0703038 DO - 10.1038/sj.bjp.0703038 ID - Rodrigues2000 ER - TY - JOUR AU - Soares, A. C. AU - Leite, R. AU - Tatsuo, M. A. AU - Duarte, I. D. PY - 2000 DA - 2000// TI - Activation of ATP-sensitive K(+) channels: mechanism of peripheral antinociceptive action of the nitric oxide donor, sodium nitroprusside JO - Eur J Pharmacol VL - 400 UR - https://doi.org/10.1016/S0014-2999(00)00355-1 DO - 10.1016/S0014-2999(00)00355-1 ID - Soares2000 ER - TY - JOUR AU - Chi, X. X. AU - Jiang, X. AU - Nicol, G. D. PY - 2007 DA - 2007// TI - ATP-sensitive potassium currents reduce the PGE2-mediated enhancement of excitability in adult rat sensory neurons JO - Brain Res VL - 1145 UR - https://doi.org/10.1016/j.brainres.2007.01.103 DO - 10.1016/j.brainres.2007.01.103 ID - Chi2007 ER - TY - JOUR AU - Andreev, N. AU - Urban, L. AU - Dray, A. PY - 1994 DA - 1994// TI - Opioids suppress spontaneous activity of polymodal nociceptors in rat paw skin induced by ultraviolet irradiation JO - Neuroscience VL - 58 UR - https://doi.org/10.1016/0306-4522(94)90456-1 DO - 10.1016/0306-4522(94)90456-1 ID - Andreev1994 ER -