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Figure 1 | Molecular Pain

Figure 1

From: Elevated interleukin-8 enhances prefrontal synaptic transmission in mice with persistent inflammatory pain

Figure 1

Levels of IL-8 in the brain following hind-paw CFA injection. (A) There was a significant increase in the IL-8 concentration in the ACC at d1, d3, d5, and d7 after CFA injection compared with saline injection (n = 6 in each time point). (B) There was a significant increase in the IL-8 concentration in the SSC at d1 but no difference at d3, d5, and d7 after CFA injection compared with saline injection (n = 6 in each time point). (C) There was a significant increase in the IL-8 concentration in the dorsal horn of lumbar spinal cord at d1, d3, d5, and d7 after CFA injection compared with saline injection (n = 6 in each time point). ** P < 0.01 compared with saline controls.

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