Table 2 Major animal models for the study of neuropathic pain
From: Translational investigation and treatment of neuropathic pain
Classification | Name of model |
|---|---|
Peripheral NP | Neuroma model |
| Â | Chronic constriction injury model (CCI) |
| Â | Partial sciatic nerve ligation model (PSL or Seltzer |
| Â | model) |
| Â | L5/L6 spinal nerve ligation model (SNL) |
| Â | Spared nerve injury |
| Â | Sciatic cryoneurolysis model (SCN) |
| Â | Inferior caudal trunk resection model (ICTR) |
| Â | Sciatic inflammatory neuritis model (SIN) |
| Â | Postherpetic neuralgia model (PHN) |
| Â | Diabetic neuropathic pain model |
| Â | Drugs-induced peripheral neuropathy model |
| Â | Bone cancer pain models |
| Â | HIV-induced neuropathy model |
| Â | Trigeminal Neuralgia model |
| Â | Orofacial pain model |
Central NP | Excitotoxic spinal cord injury (ESCI) |
| Â | Photochemical SCI model |
| Â | Weight-drop or contusive SCI (Allen's Model) |
| Â | Spinal hemisection |