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Figure 6 | Molecular Pain

Figure 6

From: Progesterone produces antinociceptive and neuroprotective effects in rats with microinjected lysophosphatidic acid in the trigeminal nerve root

Figure 6

Effects of progesterone treatment (16 mg/kg/day) upon P0 expression. (A) Vehicle treatment did not affect the LPA-induced decreases in P0 expression in the trigeminal nerve root compared with naïve rats on postoperative day 5. However, decreased P0 expression, produced by LPA injection, was recovered following treatment with progesterone. (B) Western blot analysis confirmed that LPA injections cause a decrease in the 27 kDa band for P0, which was recovered by treatment with progesterone. GAPDH was used as a loading control. (C) Quantitative analyses of western blotting data. * P < 0.05, naive- vs. LPA/vehicle-treated group. # P < 0.05, LPA/vehicle-treated group vs. LPA/progesterone-treated group. Scale bar, 50 μm.

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Molecular Pain

ISSN: 1744-8069

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