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Figure 3 | Molecular Pain

Figure 3

From: Reduction of voltage gated sodium channel protein in DRG by vector mediated miRNA reduces pain in rats with painful diabetic neuropathy

Figure 3

a. Na V 1.7 levels in DRG of diabetic animals inoculated with QHmiNa V demonstrates reduction in protein compared to QHmiSc 4 weeks after inoculation (*** p < 0.005). Data presented as ratio to β-actin (βa). b. In situ hybridization using a probe specific for NaV1.7 in DRG from diabetic animals, without treatment or inoculated with QHmiSc or QHmiNaV as indicated. A sense probe showed no staining. The average optical density of DRG neurons in each condition was determined using a PC based image analysis program (MCID). * p < 0.05; ** p < 0.01.

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