Skip to main content
Figure 3 | Molecular Pain

Figure 3

From: Imiquimod enhances excitability of dorsal root ganglion neurons by inhibiting background (K2P) and voltage-gated (Kv1.1 and Kv1.2) potassium channels

Figure 3

Antagonistic effect of IQ on TREK1 and TRAAK, K 2P channel. A, C Inhibitory effect of IQ on TREK1 (A) and TRAAK (C) channels as shown by instant I-V relationship. B, D Average % of remaining currents at each concentration of IQ on TREK1 (B) and TRAAK (D) channels. Fitted line was used to obtain IC50 (TREK1, 81.1 μM; TRAAK, 181.7 μM) of IQ on K2P channels. Error bars indicate S.E.M.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us