Figure 6

Cre-mediated deletion of β and γ ENaC subunits in DRG neurons in mice. a) PCR detection of the Cre recombinase band in genomic DNA from heterozygous Nav1.8-Cre (left) and Advillin-Cre (right) mice. b) Detection of floxed and WT bands in WT, heterozygous and homozygous βENaC^flox/flox mice (top) and of the KO band in the DRG but not the ear tissue of Nav1.8-Cre mice crossed to homozygous βENaC^flox/flox (bottom). c) detection of floxed and WT bands in WT, heterozygous and homozygous γENaC^flox/flox mice (top) and of the KO band in the DRG but not the ear tissue of Advillin-Cre mice crossed to homozygous γENaC^flox/flox (bottom).