From: Enhanced excitability of small dorsal root ganglion neurons in rats with bone cancer pain
 |  | RMP | Rin | CT | TP | TP rise rate | AP amplitude | AP overshot | AP duration | AHP amplitude | AHP80% duration | AP frequency |
---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  | mV | MΩ | pA | mV | v/s | mV | mV | ms | mV | ms | Spikes/s |
CT < 50 pA | Naïve | -50.6 ± 0.5 (29) | 654.0 ± 20.1 (33) | 29.8 ± 2.0 (29) | -27.6 ± 0.8 (38) | 0.8 ± 0.1 (30) | 101.8 ± 1.9 (34) | 55.9 ± 1.4 (34) | 44.6 ± 2.9 (30) | 19.2 ± 0.8 (40) | 17.6 ± 1.1 (35) | 20.5 ± 1.8 (30) |
 | PBS | -50.3 ± 0.7 (18) | 634.5 ± 28.5 (13) | 28.9 ± 2.2 (18) | -27.8 ± 0.8 (29) | 0.7 ± 0.1 (24) | 103.4 ± 1.8 (24) | 55.5 ± 1.6 (24) | 43.2 ± 2.6 (23) | 18.9 ± 1.3 (25) | 17.7 ± 1.4 (21) | 20.6 ± 2.3 (14) |
 | MRMT-1 | -45.6 ± 0.5 (52) *** | 546.3 ± 15.3 (60) *** | 20.9 ± 1.5 (44) *** | -30.7 ± 0.6 (55) ** | 0.9 ± 0.1 (45) * | 94.2 ± 1.9 (55) ** | 45.7 ± 1.9 (47) *** | 34.3 ± 1.4 (54) *** | 14.7 ± 0.7 (51) *** | 14.6 ± 0.6 (49) * | 31.4 ± 1.9 (32) *** |
 | HK | -50.5 ± 0.6 (13) | 638.1 ± 24.9 (19) | 28.9 ± 2.4 (13) | -26.6 ± 1.0 (23) | 0.7 ± 0.1 (13) | 102.6 ± 2.6 (16) | 54.7 ± 1.7 (16) | 44.7 ± 3.1 (16) | 19.7 ± 1.3 (11) | 18.2 ± 1.7 (13) | 20.3 ± 2.6 (12) |
 | Naïve | -51.7 ± 1.1 (12) | 593.0 ± 22.3 (14) | 85.0 ± 3.3 (13) | -20.1 ± 0.7 (19) | 1.9 ± 0.2 (11) | 104.7 ± 3.4 (17) | 55.1 ± 1.9 (17) | 24.5 ± 2.1 (15) | 19.7 ± 1.5 (16) | 10.6 ± 1.4 (16) | 10.5 ± 1.7 (15) |
CT50 ~100 pA | PBS | -51.1 ± 0.6 (7) | 594.6 ± 25.4 (6) | 86.4 ± 4.0 (7) | -19.9 ± 1.5 (6) | 2.0 ± 0.3 (5) | 105.1 ± 4.3 (6) | 56.5 ± 3.1 (6) | 24.0 ± 1.9 (6) | 20.2 ± 2.6 (7) | 11.2 ± 1.7 (7) | 13.8 ± 2.2 (6) |
 | HK | -52.6 ± 1.5 (11) | 596.9 ± 26.4 (7) | 85.5 ± 2.7 (11) | -20.0 ± 1.1 (10) | 2.0 ± 0.2 (10) | 104.0 ± 2.4 (10) | 56.0 ± 2.6 (9) | 24.0 ± 1.7 (8) | 19.7 ± 2.1 (8) | 10.7 ± 1.5 (9) | 12.2 ± 3.4 (9) |
 | MRMT-1 | -48.6 ± 0.5 (16) ** | 486.5 ± 25.8 (17) ** | 72.2 ± 4.0 (16) * | -23.4 ± 1.0 (17) ** | 2.3 ± 0.2 (14) | 98.7 ± 2.6 (17) | 46.1 ± 2.9 (15) * | 22.1 ± 1.2 (17) | 14.4 ± 1.3 (17) * | 11.4 ± 1.0 (17) | 19.3 ± 3.2 (12) * |
CT > 100 pA | Naïve | -54.6 ± 2.1 (7) | 550.5 ± 40.8 (9) | 157.9 ± 12.6 (7) | -16.6 ± 1.0 (8) | 5.4 ± 1.1 (5) | 103.7 ± 3.6 (7) | 54.1 ± 3.3 (5) | 17.5 ± 3.2 (6) | 10.8 ± 1.3 (8) | 6.3 ± 0.6 (6) | 7.1 ± 3.4 (8) |
 | PBS | -54.1 ± 1.9 (7) | 556.6 ± 35.3 (7) | 158.6 ± 14.6 (7) | -18.8 ± 0.8 (9) | 5.1 ± 0.7 (5) | 107.9 ± 4.8 (7) | 56.7 ± 3.7 (6) | 15.1 ± 1.1 (6) | 10.9 ± 1.8 (6) | 6.1 ± 0.5 (5) | 6.8 ± 2.9 (8) |
 | HK | -54.2 ± 1.6 (6) | 552.0 ± 28.5 (6) | 163.3 ± 13.2 (6) | -17.0 ± 1.2 (7) | 5.1 ± 1.2 (5) | 106.9 ± 6.3 (7) | 56.2 ± 2.4 (6) | 17.0 ± 4.6 (6) | 10.6 ± 1.8 (6) | 6.3 ± 0.6 (6) | 7.3 ± 2.6 (6) |
 | MRMT-1 | -51.2 ± 0.9 (13) | 508.1 ± 24.9 (12) | 161.7 ± 16.6 (9) | -20.2 ± 1.4 (9) | 5.0 ± 0.9 (7) | 103.3 ± 4.9 (10) | 54.9 ± 2.6 (8) | 13.9 ± 1.4 (9) | 9.0 ± 1.39 (10) | 6.3 ± 0.9 (7) | 10.0 ± 4.3 (8) |