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Figure 3 | Molecular Pain

Figure 3

From: Lidocaine patch (5%) is no more potent than placebo in treating chronic back pain when tested in a randomised double blind placebo controlled brain imaging study

Figure 3

Pain for treated and observed groups, and pain when treated group was subdivided based on pain of CBP decreasing (CBPd) or persisting (CBPp) after 2 weeks. A. Pain at baseline and after 2-weeks (visual analog score, VAS, 0-10 score) in CBP patients who received no interventions or treatment instructions, CBP observed (n = 15), in contrast to the patients who participated in the clinical trial for an ineffective treatment, CBP treatment (n = 30). The two groups started at a similar intensity of back pain but only the CBP treatment group showed decrease in back pain after two weeks. Error bars represent SEMs. * p ≪ 0.05. B. Back pain intensity, in CBPd and CBPp groups, as a function of treatment duration. A median split shows that on average the group that showed absolute pain change more than the median had significantly lower pain at the 2 week time point.

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