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Figure 1 | Molecular Pain

Figure 1

From: Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation

Figure 1

Characterization of five distinct compounds as TRPM8 antagonists. A) chemical structures of antagonists used in the study. B) Concentration dependent effects of antagonists on menthol-induced intracellular calcium increase in CHO cells stably expressing rat TRPM8. C) Concentration dependent effects of antagonists on cold (10°C)-induced intracellular calcium increase in CHO cells stably expressing rat TRPM8. Each data point in the graph are average ± S.D. of an experiment conducted in triplicate.

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Molecular Pain

ISSN: 1744-8069

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