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Figure 1 | Molecular Pain

Figure 1

From: Carrageenan induced phosphorylation of Akt is dependent on neurokinin-1 expressing neurons in the superficial dorsal horn

Figure 1

Micrographs illustrate typical lumbar dorsal horn staining for NK1 receptor in animals pretreated with spinal Sap (A) or SSP-Sap (B) 10 days prior to perfusion. The majority of the NK1R staining, including staining of almost all large somata, is missing in superficial dorsal horn after the SSP-Sap pretreatment. Size marker = 100 μm. C. Graphs show mean pixel count in laminae I-III and in laminae IV-V following the different spinal pretreatments. *** = p ≤ 0.0001 N = 3 for BSA pretreatment and 8 each for Sap and SSP-Sap.

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