Skip to main content
Figure 5 | Molecular Pain

Figure 5

From: Contribution of microglia and astrocytes to the central sensitization, inflammatory and neuropathic pain in the juvenile rat

Figure 5

Effect of astrocyte toxin, gap junction blocker and JNK inhibitor on neuronal excitation. Effect of the astroglial toxin L-alpha-aminoadipate (L-α-AA, 1 mM) (A), a gap junction blocker carbenoxolone (100 μM) (B) and the JNK inhibitor SP600125 (10 μM) (C) on neuronal excitation in control rats, rats injected with complete Freund adjuvant (CFA), and rats subjected to peripheral nerve injury (PNI). Data are expressed as % inhibition of the mean intensity of optical response during the preincubation period. *P < 0.05, **P < 0.01.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us