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Figure 1 | Molecular Pain

Figure 1

From: Milnacipran inhibits glutamatergic N-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

Figure 1

Milnacipran suppresses NMDA-induced thermal hyperalgesia (B) or desipramine + NMDA (C) on the paw withdrawal latency against thermal nociceptive stimuli. Thermal hyperalgesia was induced by intrathecal injection of NMDA. Saline or each drug was injected 15 min before NMDA. Paw withdrawal latencies are expressed as mean ± SEM for six rats in each group. * P < 0.05 compared with saline-treated group at each time point by a Student-Newman-Keuls post hoc after two-way ANOVA.

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Molecular Pain

ISSN: 1744-8069

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