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Figure 8 | Molecular Pain

Figure 8

From: Regulation of Wnt signaling by nociceptive input in animal models

Figure 8

Up-regulation of Wnt signaling proteins in the neuropathic pain model. A. Neuropathic pain was induced 1 week post L5 spinal nerve ligation (SNL, n = 6). Mice with sham operation (without SNL, n = 6) were used as controls. B-F. Wnt3a (A), ABC (B), TBC (C), Wnt5a (D), and Ror2 C (E) proteins in the ipsilateral (ipsi) and contralateral (contra) sides of the SCDH at 7 days after unilateral L5 spinal nerve ligation (SNL). Compared with the contra side, significant increases in the levels of Wnt signaling proteins were detected in the ipsi side of SNL but not control mice (n = 3). Data are summarized in graphs at right (**, p < 0.01; *, p < 0.05; #, p > 0.05; student’s t-test).

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