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Figure 1 | Molecular Pain

Figure 1

From: Activation of extracellular signal-regulated protein kinase 5 is essential for cystitis- and nerve growth factor-induced calcitonin gene-related peptide expression in sensory neurons

Figure 1

Cystitis increased CGRP mRNA and protein levels in L6 DRG. After CYP treatment for 48 h, the CGRP expression was examined in L6 DRG by immunohistochemistry (A-C) and real-time PCR (D). CGRP was largely expressed in small diameter sensory neurons (A, B). The average number of DRG neurons per unit area expressing CGRP was significantly increased post CYP treatment (C). The relative level of CGRP mRNA was also increased in L6 DRG during cystitis (D). Bar = 80 μm. *, p < 0.05 vs control. n = 5-6 animals for each group.

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Molecular Pain

ISSN: 1744-8069

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