Figure 5From: Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain Resveratrol blocks IL-6 induced signaling in sensory neurons. TG neuron cultures were pre-treated with resveratrol (100 μM, 15 min) followed by subsequent co-treatment with IL-6 (50 ng/ml, 15 min). Western blot for eIF4E (A) and ERK (B) from TG neurons treated with IL6 and/or resveratrol. Resveratrol blocked IL-6 mediated phosphorylation of eIF4E and ERK in TG cultures.Back to article page