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Figure 2 | Molecular Pain

Figure 2

From: Role of capsaicin-sensitive C-fiber afferents in neuropathic pain-induced synaptic potentiation in the nociceptive amygdala

Figure 2

Effect of neonatal capsaicin treatment on allodynic responses in rats at 7–9 days after unilateral spinal nerve ligation. Abscissa, the time point at which the measurement was made (day after operation); ordinate, 50%-paw withdrawal threshold estimated according to the responses to von Frey filament stimulation of the right (filled markers) and left (open markers) hindpaw. Nerve ligation was performed on the left spinal nerve for 32 rats. Circles represent the data from capsaicin-treated rats, and triangles indicate the values from the vehicle-treated group. Mean ± SEM. **, P < 0.01 in all comparisons vs. pre-operation values, values for the right hindpaw of both capsaicin- and vehicle-treated rats and values for both right and left hindpaw of the non-nerve ligated (non SNL) rats (one-way ANOVA followed by Bonferroni post-hoc correction). The numbers in parentheses indicate the number of rats.

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