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Figure 8 | Molecular Pain

Figure 8

From: The majority of dorsal spinal cord gastrin releasing peptide is synthesized locally whereas neuromedin B is highly expressed in pain- and itch-sensing somatosensory neurons

Figure 8

Nmb is not expressed in DRG neurons responding to innocuous thermal or mechanical stimuli. (A-D) FISH for Nmb (red) and TrpM8 (green), a marker of neurons responding to innocuous cold stimuli. (E-H) FISH for Nmb (red) and TrkB (green), a marker of Aδ LTMRs. (I-L) FISH for Nmb (red) and TH (green), a marker of a population of intermediately adapting C fiber LTMRs. (M-P) FISH for Nmb (red) and TrkC (green), a marker of slowly adapting mechanoreceptors and proprioceptors. Scale bar = 50 μm.

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