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Figure 2 | Molecular Pain

Figure 2

From: CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy

Figure 2

Molecular dynamics (MD) simulations of wild type and mutant CBD3 peptides. Conformational change experienced by (A) wild type CBD3 and (C) CBD3A6K mutant peptides over the course of multiple 10 ns MD simulations. Snapshots at 0, 5 and 10 ns of stereo pairs for (B) wild type and (D) mutant peptides are shown in capped-sticks representation, color-coded by atom type (C, N, and O in green, blue and red). The overall structure of the peptide is depicted in ribbon representation. RMSD, root mean square deviation (in angstroms)

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