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Figure 2 | Molecular Pain

Figure 2

From: Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice

Figure 2

Neither cisplatin nor paclitaxel induces acute mechanical and cold hypersensitivity. Mice were intraperitoneally administered vehicle, cisplatin (5 mg/kg; A, B), or paclitaxel (6 mg/kg; C, D), and 2 h later the 50% withdrawal threshold to mechanical stimulation ( A, C) and the escape behaviors in response to cold stimulation ( B, D) were evaluated. Data are presented as the means ± S.E.M. of 6 mice.

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