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Figure 3 | Molecular Pain

Figure 3

From: Peripheral nerve injury increases glutamate-evoked calcium mobilization in adult spinal cord neurons

Figure 3

Calcium responses elicited by glutamate. ( A.- B.) Average peak Ca2+ responses are repeatable and concentration dependent. Slices prepared from 4–6 wk CD-1 mice were superfused with aCSF at 1 ml/min. Scale bar: horizontal, Δ340/380 = 0.1; vertical, time = 60 s. Data represent average ± SEM. A. Representative tracings and average peak Ca2+ responses to 10-s pulses of 1 mM glutamate spaced at 10 min intervals. Glutamate elicited repeatable [Ca2+]i transients. N = 4 slices. B. Representative tracings and average peak Ca2+ responses to increasing glutamate concentrations. N = 3 slices.

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