Effects of NGF and GDNF on NMDA-induced currents in spinal SG neurons. Representative traces of NMDA (50 μM)-induced currents in the absence and presence of 0.1 μg/ml NGF (A) or GDNF (B) in wild-type (WT) and Y1472F-KI (YF)mice are shown. The holding potentials were −40 mV. Data (mean ± SEM, n = 4 or 5) are expressed as relative current amplitude induced by NMDA together with NGF or GDNF to that by NMDA alone. *P < 0.05 vs. NMDA alone.