Skip to main content
Figure 8 | Molecular Pain

Figure 8

From: Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection

Figure 8

Effect of SA repeated treatment (2 mg/kg, i.p.) on spinal astrocytes in mice receiving saline or formalin into the hind-paws. GFAP immunoreactivity (GFAP-ir) is shown in the ipsilateral dorsal horn 3 (B and C) and 7 (D and E) days post-saline (A) or formalin. “F” and ‘G” represent examples of resting and activated astrocytes morphology, respectively. Quantitative analysis of percentage of hypertrophic astrocytes on the total cell number in L4-L6 spinal cord sections is shown in “H”. Data are expressed as mean ± S.E.M of 3 mice. * and · indicate statistically significant differences vs veh/saline. ° indicates statistically significant differences vs veh/form 7 days after formalin injection, one-way ANOVA, Tukey post hoc).

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us