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Figure 9 | Molecular Pain

Figure 9

From: Salvinorin A reduces mechanical allodynia and spinal neuronal hyperexcitability induced by peripheral formalin injection

Figure 9

Effect of SA (2 mg/kg, ip) on i-NOS expression (A) and IL-10 levels (C) in mice receiving saline or formalin into the hind paw (3 and 7 days). Data are expressed as mean ± S.E.M (n = 3) in “A” * indicates significant differences vs veh/saline and # indicates significant differences vs veh/form (P <0.05, t-test). In “C” ** indicates significant differences vs veh/saline and ° indicates statistically significant differences vs veh/form (P <0.05, t-test). “B” represents iNOS expression up-regulation in the ipsilateral dorsal horn. Double labeling shows the iNOS expression in microglia. “D” represents IL-10 levels up-regulation in the ipsilateral dorsal horn. Double labeling shows the IL-10 level in astrocytes.

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Molecular Pain

ISSN: 1744-8069

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