Diagrams showing the number of epidermal CGRP-IR fibers (mm2
) in a group. The lateral area has a significantly lower number of CGRP-IR fibers compared to the medial area at 2 weeks PO, which normalizes at week 5. At 10 weeks PO there is no significant difference between the medial, center and lateral area of the hind paw glabrous skin of the SNI treated animals. (n = 6) One-way ANOVA with post Turkey test *: P < 0.05, **:P < 0.01, ***:P < 0.001.