Figure 4
From: Prostaglandin metabolite induces inhibition of TRPA1 and channel-dependent nociception
Homologous and heterologous inhibition evoked by 100 μM 15d-PGJ 2 vs. 100 μM AITC. A pre-pulse of 100 μM 15d-PGJ2 desensitized subsequent responses to 100 μM AITC (A) and (B). Similarly, 100 μM AITC desensitized subsequent responses to 100 μM 15d-PGJ2 and 100 μM AITC. Interstimulus intervals of 4–8 minutes were tested (8 min shown in A-D). Traces show mean ± SEM of 10–30 neurons.