Figure 4
From: Sensory discrimination between innocuous and noxious cold by TRPM8-expressing DRG neurons of rats
Inhibition by cooling temperatures of voltage-activated outward currents in TTXs/TRPM8 and TTXr/TRPM8 DRG neurons. A) Sample traces of voltage-activated outward currents in a TTXs/TRPM8 cell recorded at 24°C (left) and 10°C (middle). The right panel is the digital subtraction between the two temperatures, showing the cold-susceptible component of the voltage-activated outward currents. B) Summary of the experiments illustrated in A for TTXs/TRPM8 cells. C) Summary of the voltage-activated outward currents at 24°C and 10°C in TTXr/TRPM8 cells. Data are mean ± SEM.