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Figure 5 | Molecular Pain

Figure 5

From: Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn

Figure 5

Nav1.7 expression in spinal cord dorsal horn. Sections of spinal cord were labeled for IB4 (green), CGRP (blue) and Nav1.7 (red). A. IB4 labeling is prominent in lamina IIi , while CGRP immunoreactivity is localized to lamina I and IIo. Robust Nav1.7 immunolabeling is present within lamina I and II, and exhibits co-localization with IB4 (yellow) and with CGRP (magenta). There is limited overlap of IB4 and CGRP in the superficial lamina. B. Increased magnification of IB4, CGRP and Nav1.7 labeling in superficial lamina of dorsal horn.

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