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Table 1 Expression of cytokines in rat lymph node lysates draining normal (untreated) and inflamed (2 h CFA-treated) paws

From: JAK-STAT1/3-induced expression of signal sequence-encoding proopiomelanocortin mRNA in lymphocytes reduces inflammatory pain in rats

Cytokine

Untreated

Inflamed

CINC-2

25.33 ± 7.371

29.67 ± 6.0286

CINC-3

13.33 ± 1.155

19.33 ± 6.028

NGFβ

45.67 ± 6.658

51.76 ± 4.509

CNTF

16.67 ± 3.786

18.33 ± 3.055

Fractalkine

26.67 ± 14.01

28.67 ± 0.577

GM-CSF

15.33 ± 9.074

21.00 ± 2.646

IFN-γ

20.33 ± 5.508

23.67 ± 0.577

IL-10

9.00 ± 8.899

15.00 ± 4.583

IL-1α

12.00 ± 8.718

18.67 ± 0.577

IL-1β

12.00 ± 3.000

19.33 ± 2.309*

IL-4

10.50 ± 0.707

14.67 ± 1.155*

IL-6

9.00 ± 4.359

17.00 ± 8.888

Leptin

16.33 ± 11.240

25.00 ± 0.000

LIX

14.67 ± 11.370

24.00 ± 3.464

MCP-1

25.67 ± 6.807

60.00 ± 35.930

MIP-3alpha

13.67 ± 6.807

22.33 ± 10.500

TIMP-1

32.33 ± 11.930

49.67 ± 9.018

TNF-alpha

17.00 ± 1.732

24.67 ± 13.500

VEGF

30.00 ± 5.196

33.00 ± 10.390

  1. *, unpaired t test with Welch’s correction (P < 0.05).
  2. Data are expressed as percentages of IgG expression in mean ± SD,
  3. n = 3 animals per group.