The effects of LV-shp300 and C646 on p300 expression in the lumbar spinal cord in rats . A: Expression of mRNAs for p300 in the lumbar spinal cord in all rats. The β-actin fragment was used as an internal control. B: The mean (±SEM) of integral optical density (IOD) of P300/β-actin in rats on mRNA level, n = 5. C: Expression of protein p300 in the lumbar spinal cord in all rats. D: The mean (±SEM) of IOD of P300/PCNA in all rats on protein level, n = 5. S: sham-operated rats; NS: NS-treated CCI rats; NC: LV-NC-treated CCI rats; shp300: LV-shp300-treated CCI rats. C37: C37-treated CCI rats; C646:C646-treated CCI rats. *P < 0.05 vs. sham-operated group; #P < 0.05 vs. NS and NC-treated groups.