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Figure 5 | Molecular Pain

Figure 5

From: Upregulation of cystathionine beta-synthetase expression by nuclear factor-kappa B activation contributes to visceral hypersensitivity in adult rats with neonatal maternal deprivation

Figure 5

NaHS reduced distention threshold. Intrathecal (i.t.) injection of NaHS significantly attenuated the distention threshold in a dose-dependent fashion. NaHS with different concentrations was injected in a volume of 30 μl. The same volume of normal saline (NS) was injected (i.t.) as control. (A) NaHS at 0.01 nM did not produce any effect on distention threshold compared with NS group. (B) NaHS at 0.1 nM significantly reduced distention threshold compared with NS group. (C) NaHS at 1 nM remarkably reduced distention threshold compared with NS group. n=6 rats for each group. *p<0.05.

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