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Figure 1 | Molecular Pain

Figure 1

From: P2X7 receptors in satellite glial cells mediate high functional expression of P2X3 receptors in immature dorsal root ganglion neurons

Figure 1

P2X3Rs are expressed in a higher percentage of DRG neurons in immature rats. (A) Immunocytochemical staining of P2X3Rs and P2X7Rs in DRGs of P6 and adult rats. P2X3R labels (red) were found only in neurons; P2X7R labels (green) were found only in SGCs. (Scale bars: P2X3R, P6 = 40 μm, Adult = 50 μm; P2X7R, P6 = 25 μm, Adult = 30 μm) (B) Percentage of DRG neurons expressing P2X3Rs decreases significantly during postnatal development (P6 rats: 74.83 ± 2.03%, n = 3; adult rats: 43.45 ± 5.03%, n = 3. Student t-test, *P < 0.05)

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Molecular Pain

ISSN: 1744-8069

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