Skip to main content
Figure 3 | Molecular Pain

Figure 3

From: Proteomic and functional annotation analysis of injured peripheral nerves reveals ApoE as a protein upregulated by injury that is modulated by metformin treatment

Figure 3

ApoE expression is increased in the sciatic nerve following PNI and is induced by metformin. A) Rat sciatic nerves (n = 6) were taken 21 days following SNL surgery and ApoE was assessed by Western blot. B) Mouse sciatic nerves (n = 6) were taken 21 days following SNI surgery and ApoE was assessed by Western blot. C) Mice were treated for 7 days with 200 mg/kg metformin and sciatic nerves were removed and assessed for ApoE expression (n = 6). βIII tubulin was used as a loading control in all studies. ** p < 0.01, *** p < 0.001.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us