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Figure 4 | Molecular Pain

Figure 4

From: Role of voltage gated Ca2+ channels in rat visceral hypersensitivity change induced by 2,4,6-trinitrobenzene sulfonic acid

Figure 4

Summary data of the mean AWR to CRD following TNBS in rats treated with vehicle or nimodipine and vehicle or SNX-482. A. The AWR score significantly increased at distension volume at 1.0 2.0 and 3.0 ml 4 days following intracolonic TNBS compared with control rats (n = 9, # p < 0.05) indicating the development of visceral hyperalgesia. There was a significantly decrease in the AWR in the TNBS treated rats that received nimodipine (n = 9, * P < 0.05) and there was no difference in the AWR in the rats that received vehicle. B. The AWR score significantly increased at distension volume at 1.0 2.0 and 3.0 ml 4 days following intracolonic TNBS compared with control rats (n = 9, # p < 0.05). There was a significantly decrease in the AWR in the TNBS treated rats that received SNX-482 (n = 9, * P < 0.05) and there was no difference in the AWR in the rats that received vehicle.

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Molecular Pain

ISSN: 1744-8069

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