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Figure 3 | Molecular Pain

Figure 3

From: Enhancement by interleukin-1β of AMPA and NMDA receptor-mediated currents in adult rat spinal superficial dorsal horn neurons

Figure 3

Tetrodotoxin (TTX) reduced the AMPA- but not NMDA-induced current amplitude increase produced by IL-1β . (A) Recordings of AMPA-induced currents in the absence and presence of IL-1β in Krebs solution containing TTX (0.5 μM); they were obtained from the same neuron. (B) Recordings of NMDA-induced currents in the absence and presence of IL-1β in Krebs solution containing TTX (0.5 μM); they were obtained from the same neuron. (C) The averaged peak amplitude of AMPA (left, n = 7)- and NMDA (right, n = 7)-induced currents in the presence of IL-1β (black bar), relative to those before the application of IL-1β (control, open bar), in Krebs solution containing TTX.

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Molecular Pain

ISSN: 1744-8069

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