Figure 4

AMPA- but not NMDA-induced current amplitude increase by IL-1β depended on extracellular Ca²⁺. (A) Recordings of AMPA-induced currents in the absence and presence of IL-1β in a nominally Ca²⁺-free Krebs solution; they were obtained from the same neuron. (B) Recordings of NMDA-induced currents in the absence and presence of IL-1β in a nominally Ca²⁺-free Krebs solution; they were obtained from the same neuron. (C) Averaged peak amplitude of AMPA (left, n = 5)- or NMDA (right, n = 7)-induced currents in the presence of IL-1β (black bar), relative to those in the absence of IL-1β (control, open bar), in Ca²⁺-free solution.