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Figure 1 | Molecular Pain

Figure 1

From: Electroacupuncture improves thermal and mechanical sensitivities in a rat model of postherpetic neuralgia

Figure 1

Time course of the effects of EA on RTX-induced thermal hypoalgesia and mechanical allodynia. A, Time course of the paw withdrawal latency to a noxious heat stimulus in vehicle- and RTX-treated rats. B, Effects of 2, 15, or 100 Hz EA, and sham EA on thermal withdrawal threshold in response to a heat stimulus applied to the left hindpaw of RTX-treated rats. EA was administered for 30 min, once every other day for 5 weeks, starting from 1 week after RTX injection, as indicated by arrows. C, Time course of mechanical withdrawal threshold in response to von Frey filaments in vehicle- and RTX-treated rats. D, Effects of 2, 15, or 100 Hz EA and sham EA on mechanical withdrawal threshold in response to von Frey filaments applied to the left hindpaw of RTX treated rats. Data are expressed as means ± SEM (n = 10 rats in each group). * P < 0.01, compared with the vehicle group; # P < 0.05, compared with the sham EA group.

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