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Figure 4 | Molecular Pain

Figure 4

From: Electroacupuncture improves thermal and mechanical sensitivities in a rat model of postherpetic neuralgia

Figure 4

Effects of EA on RTX-induced ultrastructural changes of myelinated fibers and the number of unmyelinated fibers in the sciatic nerve. A, Representative electron photomicrographs show ultrastructural changes of myelinated and unmyelinated fibers in the sciatic nerve of vehicle (a), RTX (b), RTX plus 2 Hz EA (c), RTX plus 15 Hz EA (d), RTX plus 100 Hz EA (e), and RTX plus sham EA (f) groups. Scale bar, 5 μm. Asterisk, myelinated fibers; arrow, unmyelinated fibers. B, Summary data show the area of myelin sheath of myelinated fibers in the sciatic nerve in different groups. C, Summary data show the number of unmyelinated fibers in the sciatic nerve section in different groups. Data are expressed as means ± SEM (n =3 rats in each group). *P < 0.05, compared with the vehicle group; # P < 0.05, compared with the sham EA group.

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